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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1369820Generated: October 30, 2026

3-(Trifluoromethyl)benzeneacetic acid → 2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/1369820

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzeneacetic acidHCID 67695—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 15481772—

Reaction Steps

Following General Procedure BI above and using 3-trifluoromethyl-phenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06579867B2
Source datasetuspto-grants-2003_06
ORD IDord-43676b5f28fc40a0a68fa73e1d50cf7c
Source noteuspto-grants-2003_06