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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1369830Generated: October 30, 2026

m-Tolylacetic acid → N-[(3-methylphenyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1369830

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Tolylacetic acidHCID 12121—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylphenyl)acetyl]alanine Iso-butyl EsterHCID 53803690—

Reaction Steps

Following General Procedure BI above, and using 3-methylphenylacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06579867B2
Source datasetuspto-grants-2003_06
ORD IDord-db2ef3e25fe845df80264d57054c41ae
Source noteuspto-grants-2003_06