HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Alanine ethyl ester → N-[(2-phenyl)-2-fluoroacetyl]alanine Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Alanine ethyl ester | HCID 76507 | — |
| Reactant | Fluorophenylacetic acid | HCID 102649 | — |
| Product | N-[(2-phenyl)-2-fluoroacetyl]alanine Ethyl Ester | HCID 22894970 | — |
Reaction Steps
Following General Procedure BF above, and using α-fluorophenyl acetic acid (Aldrich) and alanine ethyl ester (Aldrich), the title compound was prepared. The reaction was monitored by tlc on silica gel (Rf=0.75 in 1:1 EtOAc:hexane) and purification was by chromatography on silica gel using 1:2 ethyl acetate/hexanes as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06579867B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-7bc2523e613f45f4b3e6530a3655ed6c |
| Source note | uspto-grants-2003_06 |