HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → HCID 23444684, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | 4-Methyl-1,3-dihydro-2H-indol-2-one | HCID 12579382 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23444684 | HCID 23444684 | 88.1% |
Reaction Steps
To 2 g of 4-methyl-2-oxindole in 40 mL of glacial acetic acid in an ice bath was added 3.67 g N-iodosuccinimide. The mixture was stirred for 1 hour, diluted with 100 mL 50% acetic acid in water and filtered. The resulting white solid was dried under high vacuum to give 3.27 g (88% yield) of the title compound as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06579897B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-aaa5293947244429ba50ade071931ce2 |
| Source note | uspto-grants-2003_06 |