Magnesium → HCID 18516355, compound

Participants

Reaction Steps

A solution of 550 mg (2.0 mmol) of 7-(methoxycarbonyl-ethenyl)-1,2,3,5-tetrahydrocyclopenta[c]quinolin-4-one in 130 ml of methanol-THF 3:1 is mixed with 972 mg (40.0 mmol) of magnesium and stirred for 24 hours at room temperature. The reaction mixture is filtered over glass fibers, the filter residue is washed with dichloromethane-methanol, and the combined filtrates are concentrated by evaporation in a vacuum. Purification of the residue on silica gel yields 120 mg of product.

Provenance & Evidence