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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 137005Generated: October 26, 2026

Dimethylformamide → 3-chloro-N-[1-(3,3-difluoropiperidin-1-yl)-3-methylbutan-2-yl]-4-fluoro-N-methylbenzamide

https://huagongshe.com/reaction/137005

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTetrafluoroborateHCID 26255—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant3-Chloro-4-fluorobenzoic acidHCID 520989—
Reactant1-(3,3-difluoropiperidin-1-yl)-N,3-dimethylbutan-2-amineHCID 67772541—
Product3-chloro-N-[1-(3,3-difluoropiperidin-1-yl)-3-methylbutan-2-yl]-4-fluoro-N-methylbenzamideHCID 67773860—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-164e094ea14f4c5ba9ee9a1341201d78
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)