Formaldehyde → L-Pantothenic acid

Participants

Reaction Steps

Pantothenic acid can be prepared by chemical synthesis or via biotechnology by fermentation of suitable microorganisms in suitable nutrient solutions. DL-pantolactone is an important compound in the chemical synthesis, and is prepared in a multi-stage process from formaldehyde, isobutyl aldehyde and cyanide. In further process steps the racemic mixture is separated and D-pantolactone is condensed with β-alanine to yield D-pantothenic acid.

Provenance & Evidence