HCID 18510481, compound → HCID 9877792, compound

HRID 1370189Notes

Reaction equation

HRID 1370189 reaction equation
Br[C:2]1[C:10]2[CH:9]=[N:8][CH:7]=[CH:6][C:5]=2[N:4]2[CH2:11][CH2:12][CH2:13][C:3]=12.C(OC([N:21]1[C@H:25]([CH3:26])[CH2:24]OS1(=O)=O)=O)(C)(C)C>>[CH2:13]1[C:3]2=[C:2]([CH2:24][C@H:25]([NH2:21])[CH3:26])[C:10]3[CH:9]=[N:8][CH:7]=[CH:6][C:5]=3[N:4]2[CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 18510481HCID 18510481, compoundHCID 46172873(4R)-2,2-Dioxido-4-methyl-1,2,3-oxathiazolidine,N-BOC protected

Product 1

HCID 9877792HCID 9877792, compound

Procedure

By the same general procedure as in example 3(R)-2-(2,3-Dihydro-1H-3a,6-diaza-cyclopenta[a]inden-8-yl)-1-methyl-ethylamine was obtained from 8-Bromo-2,3-dihydro-1H-3a,6-diaza-cyclopenta[a]indene and (R)-4-Methyl-2,2-dioxo-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester as white solid.

Sources & evidence

ORD record
ord-667e775650174e9ca9fadacd7b71fb7d
Source dataset
uspto-grants-2003_06
Patent number
US06583134B2

Reaction notes

Loading…