HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 53889634, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Alanine methyl ester hydrochloride | HCID 2733257 | — |
| Reactant | N-tosyl-(s)-proline monohydrate | HCID 69463844 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 53889634 | HCID 53889634 | — |
Reaction Steps
N-(Toluene-4-sulfonyl)-L-proline hydrate was coupled to L-alanine methyl ester hydrochloride using the procedure described in Method 3. The resulting methyl ester was deesterified via hydrolysis using LiOH in THF/water to provide the title compound as a solid, mp=160.5-162.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583139B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-5e939163f4214d5a8f75551511de8aad |
| Source note | uspto-grants-2003_06 |