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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1370233Generated: October 31, 2026

Lithium Hydroxide → HCID 25552760, compound

https://huagongshe.com/reaction/1370233

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactantmethyl (2S)-2-amino-4-(methylsulfanyl)butanoateHCID 64684—
ReactantN-tosyl-(s)-proline monohydrateHCID 69463844—
SolventOxolane--water (1/1)HCID 21881883—
ProductHCID 25552760HCID 25552760—

Reaction Steps

N-(Toluene-4-sulfonyl)-L-proline hydrate was coupled to methionine methyl ester using the procedure described in Method 3. The title compound was prepared via hydrolysis of the methyl ester using LiOH in THF/water.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06583139B1
Source datasetuspto-grants-2003_06
ORD IDord-9d87548153864ad683051a88be12eb1d
Source noteuspto-grants-2003_06