HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 54472187, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Methyl valinate hydrochloride | HCID 111190 | — |
| Reactant | N-tosyl-(s)-proline monohydrate | HCID 69463844 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 54472187 | HCID 54472187 | — |
Reaction Steps
N-(Toluene-4-sulfonyl)-L-proline hydrate was coupled to L-valine methyl ester hydrochloride using the procedure described in Method 3. The title compound was prepared via hydrolysis of the methyl ester using LiOH in THF/water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583139B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-fef7a36bd4ab4720af9340d1e3fea1d1 |
| Source note | uspto-grants-2003_06 |