HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 69195542, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 53672405 | HCID 53672405 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 69195542 | HCID 69195542 | 89.3% |
Reaction Steps
) NaBH4 (0.054 mol) was added to a solution of compound (3) (0.054 mol) in methanol (300 ml). The reaction mixture was stirred overnight at RT. The precipitate was filtered off, washed with CH3OH and DIPE, then dried, yielding 18 g (89%) of (5S)-4,5-dihydro-N-[4-(hydroxyphenylmethyl)phenyl]-3-(3-pyridinyl)-5-isoxazolecarboxamide (compound 499).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583141B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-6c98d4c08ea447ffa7b01a2411eb7a9e |
| Source note | uspto-grants-2003_06 |