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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 137041Generated: October 30, 2026

Acetic Acid → 4-{4-[5-(4-Chlorophenyl)pyridin-2-ylethynyl]phenyl}-1-cyclopropylmethylpiperidin-4-ol

https://huagongshe.com/reaction/137041

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantCyclopropanecarboxaldehydeHCID 123114—
ReactantTriacetoxyborohydrideHCID 2724942—
ReactantHCID 69058833HCID 69058833—
Product4-{4-[5-(4-Chlorophenyl)pyridin-2-ylethynyl]phenyl}-1-cyclopropylmethylpiperidin-4-olHCID 57845320—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-409557c1571f4acc967196a2723244a1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)