HCID 18511494, compound → HCID 18511541, compound

HRID 1370515Notes

Reaction equation

HRID 1370515 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:11][C:12](O)=O)[CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1.[ClH:15].NC1[S:18][C:19]2[CH:25]=[CH:24][CH:23]=[C:22](Cl)[C:20]=2[N:21]=1>>[Cl:15][C:23]1[CH:24]=[CH:25][C:19]2[S:18][C:12]([CH2:11][C:4]3[CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=[C:2]([Cl:1])[CH:3]=3)=[N:21][C:20]=2[CH:22]=1

Participants

3

Reactant 2

HCID 18511494HCID 18511494, compoundHCID 185116034-Chloro-1,3-benzothiazol-2-amine--hydrogen chloride (1/1)

Product 1

HCID 18511541HCID 18511541, compound

Procedure

5-Chloro-2-(3-chloro-5-nitro-benzyl)-benzothiazole (329) was synthesized (92%) from (3-chloro-5-nitro-phenyl)-acetic acid (328, 430 mg, 2.0 mmol) and 2-amino-4-chloro-benzothiazole hydrochloride (6, 392 mg, 2.0 mmol) in a similar manner as described in Example 8.

Sources & evidence

ORD record
ord-26b0cc3d76be46b88ee1b4f14aeed20a
Source dataset
uspto-grants-2003_06
Patent number
US06583157B2

Reaction notes

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