4-Amino-2,6-dichlorophenol → HCID 18511620, compound

HRID 1370519Notes

Reaction equation

HRID 1370519 reaction equation
Cl[C:2]1[S:3][C:4]2[CH:10]=[C:9]([O:11][C:12]([F:15])([F:14])[F:13])[CH:8]=[CH:7][C:5]=2[N:6]=1.[NH2:16][C:17]1[CH:22]=[C:21]([Cl:23])[C:20]([OH:24])=[C:19]([Cl:25])[CH:18]=1>>[Cl:23][C:21]1[CH:22]=[C:17]([NH2:16])[CH:18]=[C:19]([Cl:25])[C:20]=1[O:24][C:2]1[S:3][C:4]2[CH:10]=[C:9]([O:11][C:12]([F:15])([F:14])[F:13])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

3

Reactant 2

HCID 800374-Amino-2,6-dichlorophenolHCID 100379242-Chloro-6-(trifluoromethoxy)-1,3-benzothiazole

Product 1

HCID 18511620HCID 18511620, compound

Procedure

3,5-Dichloro-4-(6-trifluoromethoxy-benzothiazol-2-yloxy)-phenylamine was synthesized (76%) from 2-chloro-6-trifluoromethoxybenzotiazole (413) and 4-amino-2,6-dichlorophenol (Aldrich) in a similar manner as described in Example 417.

Sources & evidence

ORD record
ord-80416cb6c4eb44b188d845da9f632428
Source dataset
uspto-grants-2003_06
Patent number
US06583157B2

Reaction notes

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