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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1370522Generated: October 31, 2026

4-Amino-2-chlorophenol → 2-Chloro-N-(3-chloro-4-hydroxy-phenyl)-4-trifluoromethylbenzenesulfonamide

https://huagongshe.com/reaction/1370522

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-chlorophenolHCID 77578—
Reactant2-Chloro-4-(trifluoromethyl)benzenesulfonyl chlorideHCID 2736675—
Product2-Chloro-N-(3-chloro-4-hydroxy-phenyl)-4-trifluoromethylbenzenesulfonamideHCID 18511530—

Reaction Steps

2-Chloro-N-(3-chloro-4-hydroxy-phenyl)-4-trifluoromethyl-benzenesulfonamide was synthesized (92%) from 4-amino-2-chlorophenol (Aldrich) and 2-chloro-4-trifluoromethylbenzenesulfonyl chloride in a similar manner as described in Example 421.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06583157B2
Source datasetuspto-grants-2003_06
ORD IDord-2fcf1561437e48a78e5b0b974bece6fa
Source noteuspto-grants-2003_06