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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1370525Generated: October 26, 2026

p-(Trifluoromethoxy)benzenesulphonyl chloride → N-[3,5-Dichloro-4-(6-chloro-benzothiazol-2-yloxy)-phenyl]-4-trifluoromethoxy-benzenesulfonamide

https://huagongshe.com/reaction/1370525

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-(Trifluoromethoxy)benzenesulphonyl chlorideHCID 523102—
Reactant3,5-Dichloro-4-(6-chloro-benzothiazol-2-yloxy)-phenylamineHCID 22148776—
ProductN-[3,5-Dichloro-4-(6-chloro-benzothiazol-2-yloxy)-phenyl]-4-trifluoromethoxy-benzenesulfonamideHCID 18511631—

Reaction Steps

N-[3,5-Dichloro-4-(6-chloro-benzothiazol-2-yloxy)-phenyl]-4-trifluoromethoxy-benzenesulfonamide was synthesized (83%) from 3,5-dichloro-4-(6-chloro-benzothiazol-2-yloxy)-phenylamine (420) and 4-trifluoromethoxybenzenesulfonyl chloride (Maybridge) in a similar manner as described in Examples 70-91.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06583157B2
Source datasetuspto-grants-2003_06
ORD IDord-cb72f8075f0545339ee80e5a384331df
Source noteuspto-grants-2003_06