2-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride → HCID 18511578, compound

HRID 1370526Notes

Reaction equation

HRID 1370526 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:20])[CH:5]=[C:6]([Cl:19])[C:7]=1[O:8][C:9]1[S:10][C:11]2[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:12]=2[N:13]=1.[N+:21]([C:24]1[CH:29]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:27]=[CH:26][C:25]=1[S:34](Cl)(=[O:36])=[O:35])([O-:23])=[O:22]>>[Cl:19][C:6]1[CH:5]=[C:4]([NH:20][S:34]([C:25]2[CH:26]=[CH:27][C:28]([C:30]([F:32])([F:33])[F:31])=[CH:29][C:24]=2[N+:21]([O-:23])=[O:22])(=[O:35])=[O:36])[CH:3]=[C:2]([Cl:1])[C:7]=1[O:8][C:9]1[S:10][C:11]2[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:12]=2[N:13]=1

Participants

3

Reactant 2

HCID 27757802-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chlorideHCID 221487763,5-Dichloro-4-(6-chloro-benzothiazol-2-yloxy)-phenylamine

Product 1

HCID 18511578HCID 18511578, compound

Procedure

N-[3,5-Dichloro-4-(6-chloro-benzothiazol-2-yloxy)-phenyl]-2-nitro-4-trifluoromethyl-benzenesulfonamide was synthesized (48%) from 3,5-dichloro-4-(6-chloro-benzothiazol-2-yloxy)-phenylamine (420) and 2-nitro-4-trifluoromethylbenzenesulfonyl chloride (Aldrich) in a similar manner as described in Examples 70-91.

Sources & evidence

ORD record
ord-7649e3107ed14c6f8fa260679187d6e2
Source dataset
uspto-grants-2003_06
Patent number
US06583157B2

Reaction notes

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