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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1370542Generated: October 30, 2026

Ethyl chloroformate → 2-Cyclohexyl-2,3-dihydro-6-[4-(ethoxycarbonyl)-piperazin-1-yl]-1H-isoindol-1-one

https://huagongshe.com/reaction/1370542

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl chloroformateHCID 10928—
ReactantHCID 22180413HCID 22180413—
Product2-Cyclohexyl-2,3-dihydro-6-[4-(ethoxycarbonyl)-piperazin-1-yl]-1H-isoindol-1-oneHCID 18510832—

Reaction Steps

In the same manner as in Example 28, the title compound was prepared from the compound obtained in step (e) of Example 1 and ethoxycarbonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06583144B2
Source datasetuspto-grants-2003_06
ORD IDord-c947d0a31db24bd2a8ce9bf34062c2a4
Source noteuspto-grants-2003_06