1,1'-(3-Bromopropylidene)bisbenzene → HCID 18510887, compound

HRID 1370550Notes

Reaction equation

HRID 1370550 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:22]=[C:21]3[C:17]([CH2:18][N:19]([CH:24]4[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]4)[C:20]3=[O:23])=[CH:16][C:15]=2[Cl:30])[CH2:10][CH2:9]1)=O)(C)(C)C.[C:31]1([CH:37]([C:41]2[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=2)[CH2:38][CH2:39]Br)[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[Cl:30][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][C:14]=1[N:11]1[CH2:10][CH2:9][N:8]([CH2:39][CH2:38][CH:37]([C:41]3[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=3)[C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[CH2:13][CH2:12]1)[C:20](=[O:23])[N:19]([CH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1)[CH2:18]2

Participants

3

Reactant 2

HCID 883331,1'-(3-Bromopropylidene)bisbenzeneHCID 18510785HCID 18510785, compound

Product 1

HCID 18510887HCID 18510887, compound

Procedure

In the same manner as in Example 47, the title compound was prepared from 6-[4-(t-butoxycarbonyl)piperazin-1-yl]-5-chloro-2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one obtained in Example 45 and 3,3-diphenylpropyl bromide.

Sources & evidence

ORD record
ord-e0a87919d3dd4ec0bd154e2daf88cb43
Source dataset
uspto-grants-2003_06
Patent number
US06583144B2

Reaction notes

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