HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzyl chloride → 6-[4-(3,3-Diphenyl-1-propyl)piperazin-1-yl)-2-(3-methoxybenzyl)-2,3-dihydro-1H-isoindol-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzyl chloride | HCID 69994 | — |
| Reactant | 2,3-Dihydro-6-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-1H-isoindol-1-one | HCID 18510931 | — |
| Product | 6-[4-(3,3-Diphenyl-1-propyl)piperazin-1-yl)-2-(3-methoxybenzyl)-2,3-dihydro-1H-isoindol-1-one | HCID 18510822 | 60.6% |
Reaction Steps
In the same manner as in Example 51, the title compound (35 mg) was prepared from the compound (50 mg) obtained in Example 50 and 3-methoxybenzyl chloride (17 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583144B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-db1325561d0f40e482136aa94cbbcb15 |
| Source note | uspto-grants-2003_06 |