Boron tribromide → HCID 18510962, compound

HRID 1370566Notes

Reaction equation

HRID 1370566 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]([CH:39]=[C:40]([O:42]C)[CH:41]=1)[CH2:6][N:7]1[CH2:16][CH2:15][C:14]2[C:9](=[CH:10][C:11]([N:17]3[CH2:22][CH2:21][N:20]([CH2:23][CH2:24][CH:25]([C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)[C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)[CH2:19][CH2:18]3)=[CH:12][CH:13]=2)[C:8]1=[O:38].B(Br)(Br)Br>ClCCl>[OH:42][C:40]1[CH:39]=[C:5]([CH:4]=[C:3]([OH:2])[CH:41]=1)[CH2:6][N:7]1[CH2:16][CH2:15][C:14]2[C:9](=[CH:10][C:11]([N:17]3[CH2:18][CH2:19][N:20]([CH2:23][CH2:24][CH:25]([C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=4)[C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)[CH2:21][CH2:22]3)=[CH:12][CH:13]=2)[C:8]1=[O:38]

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 18510773HCID 18510773, compound

Product 1

HCID 18510962HCID 18510962, compoundYield 49.1%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In the same manner as in Example 131, the title compound (28 mg) was prepared from the compound (60 mg) obtained in Example 130 and a 1.0 M aqueous dichloromethane solution (0.6 ml) of boron tribromide.

Sources & evidence

ORD record
ord-0000e2f6e33a438cbafcd31762f25e18
Source dataset
uspto-grants-2003_06
Patent number
US06583144B2

Reaction notes

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