HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 4-Bromobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | p-Bromobenzenesulfonyl chloride | HCID 7396 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Bromobenzenesulfonamide | HCID 69696 | — |
Reaction Steps
The resin-bound secondary amine resin (from C) was swelled in DCM (200 mL). To the suspension was added pyridine (3.19 g) followed by 4-bromophenylsulfonyl chloride (5.1 g, 20.0 millimole) and shaken overnight. The resin was filtered and washed with 3 portions of DCM, 3 portions of methanol, 3 portions of DCM, and 3 portions of methanol. The resin was dried in vacuo overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583179B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-3b9649ab38354c5dbb37b19510d1099d |
| Source note | uspto-grants-2003_06 |