7-chloro-1H-indole → 7-Chloro-3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indole

Participants

Role	Name	HCID	Charge
Reactant	7-chloro-1H-indole	HCID 104644	—
Reactant	1-Ethyl-5-fluoroindan-1-ol	HCID 59340428	—
Product	7-Chloro-3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indole	HCID 11565881	—

Reaction Steps

Utilizing 1-ethyl-5-fluoro-indan-1-ol and 7-chloroindole, the title compound is prepared as in example 1. 90 mg (60%). NMR (400 MHz, CDCl3): δ 0.85 (t, 3H), 2.15 (m, 1H), 2.22 (m, 1H), 2.34 (m, 1H), 2.59 (m, 1H), 2.98 (m, 2H), 6.82 (t, 1H), 6.87 (m, 2H), 7.00 (m, 2H), 7.11 (d, 1H), 7.16 (d, 1H), 8.12 (s, 1H, NH).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07728150B2
Source dataset	uspto-grants-2010_06
ORD ID	ord-7a04d25028314e6e9dd1befb42518329
Source note	uspto-grants-2010_06