HCID 10208868, compound → HCID 10274722, compound

HRID 1370705Notes

Reaction equation

HRID 1370705 reaction equation
[H][H].[CH3:3][O:4][C:5]([C:7]1[N:8]=[C:9]([NH:12][C:13](=[O:40])[C@@H:14]([N:22]2[C:26](=[O:27])[C@H:25]([CH2:28][C:29]3C=CC4C(=CC=CC=4)[CH:30]=3)[NH:24][C:23]2=[O:39])[CH2:15][CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)[S:10][CH:11]=1)=[O:6]>>[CH3:3][O:4][C:5]([C:7]1[N:8]=[C:9]([NH:12][C:13](=[O:40])[C@@H:14]([N:22]2[C:26](=[O:27])[C@@H:25]([CH2:28][CH2:29][CH3:30])[NH:24][C:23]2=[O:39])[CH2:15][CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)[S:10][CH:11]=1)=[O:6]

Participants

3

Reactant 2

HCID 10208868HCID 10208868, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 10274722HCID 10274722, compound

Procedure

In yet another embodiment of Compound A-1b, R3 is naphthyl and R4 is hydrogen. An example of such a compound is (S,S)-2-[[3-cyclohexyl-2-[2,5-dioxo-4-(naphthalen-2-yl)methylimidazolidin-1-yl]propanoyl]amino]thiazole-4-carboxylic acid methyl ester.

Sources & evidence

ORD record
ord-12aaa4ec9dc84b0daa2ee4cd24e1589e
Source dataset
uspto-grants-2003_06
Patent number
US06583288B2

Reaction notes

Loading…