Toluene → HCID 178506415, compound

Participants

Reaction Steps

At −78° C., 651 mg (3.04 mmol) of (R,R)-hydrobenzoin is charged in a vessel together with 1.0 ml of abs. triethylamine (6.63 mmol) in 150 ml of abs. toluene. A solution of 425 mg (0.80 mmol) of 1,1′-bis(dichlorophosphino)ferrocene (X) in 25 ml of abs. THF is added dropwise within 2 h. Then, thawing is allowed slowly in a cooling bath over night with stirring. The solution obtained is completely freed from solvent, and the orange solid is taken up in 200 ml of abs. diethyl ether. Insolubles are separated off by filtration through a P4 frit with Celite 545® as a filtering aid. The clear orange filtrate is completely freed from solvent to obtain an orange solid. Analytical results: 1H NMR (d8-THF, 300 MHz): 7.40 (s) [8H], 7.36-7.30 (m) [6H], 7.29-7.23 (m) [4H], 7.22-7.11 (m) [6H], 5.05 (d) JH-P=8.1 Hz [2H], 4.95 (d) JH-P=9 Hz [2H], 4.82-4.60 (m) [8H]; 31P NMR (d8-THF, 121 MHz): 181.7 (s).

Provenance & Evidence