反应详情

19.2 g (0.1 mol) of the compound obtained in Step B are dissolved in 300 ml of CH2Cl2. Under argon, 65 g (7.5 eq) of manganese oxide are added in three stages (t═0: 25 g, t=3 h :25 g, and t=24 h: 15 g). The alcohol is totally oxidised after a further 24 hours. The mixture is then filtered over Celite in order to remove the mineral compounds, rinsed with CH2Cl2 and then filtered over silica to yield an oil which solidifies on cooling.

1. filtrationThe mixture is then filtered over Celite in order
2. customto remove the mineral compounds
3. washrinsed with CH2Cl2
4. filtrationfiltered over silica
5. customto yield an oil which
6. temperatureon cooling