HCID 70026837, compound → HCID 69959678, compound

HRID 1370769Notes

Reaction equation

HRID 1370769 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH:13]=[CH:14][C:15]([O:17]CC)=[O:16])=[CH:5][CH:4]=1>C(O)C.[OH-].[Na+]>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH:13]=[CH:14][C:15]([OH:17])=[O:16])=[CH:5][CH:4]=1

Participants

4

Reactant 1

HCID 70026837HCID 70026837, compound

Product 1

HCID 69959678HCID 69959678, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

8.4 g (32.8 mmol) of the ester obtained in Step D dissolved in 150 ml of ethanol in the presence of 40 ml of 2N sodium hydroxide solution are stirred for 3 hours at room temperature and overnight at reflux to yield the title acid in the form of a white solid.

Workup

  1. temperatureat reflux

Sources & evidence

ORD record
ord-d868500446ce46cc9f297e91d43f37f4
Source dataset
uspto-grants-2003_06
Patent number
US06583319B1

Reaction notes

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