Ammonium Chloride → HCID 68858129, compound

Participants

Reaction Conditions

Reaction Steps

The product from Example 6B (1.43 g, 3.67 mmoles) and NH4Cl (0.14 g, 2.57 mmoles) in ethanol (18.4 mL) and water (6.4 mL) were treated with iron powder (1.43 g, 25.7 mmoles) and heated at 80° C. for one hour. The reaction mixture was allowed to cool to room temperature, diluted with CH2Cl2 (100 mL), filtered through Celite with ethyl acetate, and the filtrate was concentrated under reduced pressure to provide the title compound which was used without further purification.

Provenance & Evidence