4-Chloro-2-fluorobenzyl bromide → HCID 86586228, compound

HRID 1370864Notes

Reaction equation

HRID 1370864 reaction equation
[CH3:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:11][CH2:12][C:13]1[CH:32]=[CH:31][C:16]([O:17][C:18]2[CH:19]=[C:20]([CH:28]=[CH:29][CH:30]=2)[O:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:15][CH:14]=1.[Cl:33][C:34]1[CH:41]=[CH:40][C:37]([CH2:38]Br)=[C:36]([F:42])[CH:35]=1>>[Cl:33][C:34]1[CH:41]=[CH:40][C:37]([CH2:38][N:11]([CH2:12][C:13]2[CH:32]=[CH:31][C:16]([O:17][C:18]3[CH:19]=[C:20]([CH:28]=[CH:29][CH:30]=3)[O:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:15][CH:14]=2)[C:3]2[CH:4]=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=2[CH3:1])=[C:36]([F:42])[CH:35]=1

Participants

3

Reactant 2

HCID 27365514-Chloro-2-fluorobenzyl bromideHCID 86586229HCID 86586229, compound

Product 1

HCID 86586228HCID 86586228, compound

Procedure

The product from Example 83B and 4-chloro-2-fluorobenzyl bromide were processed as described in Example 6B to provide the title compound.

Sources & evidence

ORD record
ord-0fd2645ada1e4b47b9547879f80757e1
Source dataset
uspto-grants-2003_06
Patent number
US06583180B2

Reaction notes

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