4-Chloro-2-fluorobenzyl bromide → HCID 18512063, compound

HRID 1370867Notes

Reaction equation

HRID 1370867 reaction equation
[CH3:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:11][CH2:12][C:13]1[CH:31]=[CH:30][C:16]([O:17][C:18]2[CH:23]=[CH:22][C:21]([CH2:24][CH2:25][C:26]([O:28][CH3:29])=[O:27])=[CH:20][CH:19]=2)=[CH:15][CH:14]=1.[Cl:32][C:33]1[CH:40]=[CH:39][C:36]([CH2:37]Br)=[C:35]([F:41])[CH:34]=1>>[Cl:32][C:33]1[CH:40]=[CH:39][C:36]([CH2:37][N:11]([CH2:12][C:13]2[CH:31]=[CH:30][C:16]([O:17][C:18]3[CH:23]=[CH:22][C:21]([CH2:24][CH2:25][C:26]([O:28][CH3:29])=[O:27])=[CH:20][CH:19]=3)=[CH:15][CH:14]=2)[C:3]2[CH:4]=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=2[CH3:1])=[C:35]([F:41])[CH:34]=1

Participants

3

Reactant 2

HCID 27365514-Chloro-2-fluorobenzyl bromideHCID 18511990HCID 18511990, compound

Product 1

HCID 18512063HCID 18512063, compound

Procedure

The product from Example 76C and 4-chloro-2-fluorobenzyl bromide were processed as described in Example 6B to provide the title compound.

Sources & evidence

ORD record
ord-e0a23e3d73874fb1a9a02fc50fc23b28
Source dataset
uspto-grants-2003_06
Patent number
US06583180B2

Reaction notes

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