HRID1370882

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID90297

1-(Bromomethyl)-2,4-difluorobenzene

C7H5BrF2

结构：C=CCOc1cc(OC)cc(Oc2ccc(CNc3cccc([N+](=O)[O-])c3C)cc2)c1

HCID18512102

未命名化合物

PRODUCTS

生成物

结构：C=CCOc1cc(OC)cc(Oc2ccc(CN(Cc3ccc(F)cc3F)c3cccc([N+](=O)[O-])c3C)cc2)c1

HCID18512090

未命名化合物

PROCEDURE

实验过程

The product from Example 90C and 2,4-difluorobenzyl bromide were processed as described in Example 6B to provide the title compound. MS (APCI+) m/z 547 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-aac1d5af83124fb5b17a0841f0e349aa
来源数据集: uspto-grants-2003_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06583180B2
来源说明: uspto-grants-2003_06

反应 SMILES

[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([CH:27]=[C:28]([O:30][CH3:31])[CH:29]=1)[O:8][C:9]1[CH:26]=[CH:25][C:12]([CH2:13][NH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[C:16]=2[CH3:24])=[CH:11][CH:10]=1)[CH:2]=[CH2:3].[F:32][C:33]1[CH:40]=[C:39]([F:41])[CH:38]=[CH:37][C:34]=1[CH2:35]Br>>[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([CH:27]=[C:28]([O:30][CH3:31])[CH:29]=1)[O:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:13][N:14]([CH2:35][C:34]2[CH:37]=[CH:38][C:39]([F:41])=[CH:40][C:33]=2[F:32])[C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[C:16]=2[CH3:24])=[CH:25][CH:26]=1)[CH:2]=[CH2:3]