1-(Bromomethyl)-2,4-difluorobenzene → HCID 86586236, compound

HRID 1370897Notes

Reaction equation

HRID 1370897 reaction equation
[CH3:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:11][CH2:12][C:13]1[CH:32]=[CH:31][C:16]([O:17][C:18]2[CH:19]=[C:20]([CH:28]=[CH:29][CH:30]=2)[O:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:15][CH:14]=1.[F:33][C:34]1[CH:41]=[C:40]([F:42])[CH:39]=[CH:38][C:35]=1[CH2:36]Br>>[F:33][C:34]1[CH:41]=[C:40]([F:42])[CH:39]=[CH:38][C:35]=1[CH2:36][N:11]([CH2:12][C:13]1[CH:32]=[CH:31][C:16]([O:17][C:18]2[CH:19]=[C:20]([CH:28]=[CH:29][CH:30]=2)[O:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:15][CH:14]=1)[C:3]1[CH:4]=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=1[CH3:1]

Participants

3

Reactant 2

HCID 902971-(Bromomethyl)-2,4-difluorobenzeneHCID 86586229HCID 86586229, compound

Product 1

HCID 86586236HCID 86586236, compound

Procedure

The product from Example 83B and 2,4 difluorobenzyl bromide were processed as described in Example 6B to provide the title compound.

Sources & evidence

ORD record
ord-b2ac188299a84d0a894c7046494477dc
Source dataset
uspto-grants-2003_06
Patent number
US06583180B2

Reaction notes

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