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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13709Generated: October 25, 2026

Methyl indole-7-carboxylate → 3-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indole-7-carboxylic acid methyl ester

https://huagongshe.com/reaction/13709

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl indole-7-carboxylateHCID 676694—
Reactant1-Ethyl-5-fluoroindan-1-olHCID 59340428—
Product3-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indole-7-carboxylic acid methyl esterHCID 11602482—

Reaction Steps

Utilizing 1-ethyl-5-fluoro-indan-1-ol and 1H-indole-7-carboxylic acid methyl ester, the title compound is prepared as in example 1. 103 mg (75%). LC-MS m/z 338.1 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728150B2
Source datasetuspto-grants-2010_06
ORD IDord-736cdd0e368242faa9ac6b54fa0a8699
Source noteuspto-grants-2010_06