Ethyl iodoacetate → Ethyl {2-[3-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenoxy]ethoxy}acetate

HRID 1370910Notes

Reaction equation

HRID 1370910 reaction equation
[CH2:1]([N:8]([CH2:19][C:20]1[CH:36]=[CH:35][C:23]([O:24][C:25]2[CH:26]=[C:27]([CH:32]=[CH:33][CH:34]=2)[O:28][CH2:29][CH2:30][OH:31])=[CH:22][CH:21]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[C:10]=1[CH3:18])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.I[CH2:38][C:39]([O:41][CH2:42][CH3:43])=[O:40]>>[CH2:1]([N:8]([CH2:19][C:20]1[CH:21]=[CH:22][C:23]([O:24][C:25]2[CH:26]=[C:27]([CH:32]=[CH:33][CH:34]=2)[O:28][CH2:29][CH2:30][O:31][CH2:38][C:39]([O:41][CH2:42][CH3:43])=[O:40])=[CH:35][CH:36]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[C:10]=1[CH3:18])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 12183Ethyl iodoacetateHCID 185122382-[3-(4-{[Benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenoxy]ethanol

Product 1

HCID 86759032Ethyl {2-[3-(4-{[benzyl(2-methyl-3-nitrophenyl)amino]methyl}phenoxy)phenoxy]ethoxy}acetate

Procedure

The product from Example 92B and ethyl iodoacetate were processed as described in Example 116A to provide the title compound.

Sources & evidence

ORD record
ord-dc5a4e5a1aad4fc392af328b2ba22874
Source dataset
uspto-grants-2003_06
Patent number
US06583180B2

Reaction notes

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