HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Phenylalanine, 1,1-dimethylethyl ester, hydrochloride (1:1) → HCID 68855290, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Phenylalanine, 1,1-dimethylethyl ester, hydrochloride (1:1) | HCID 11459563 | — |
| Reactant | 4-(4-{4-[(benzyl{2-methyl-3-[(methylsulfonyl)amino]phenyl}amino)methyl]phenoxy}phenyl)butanoic Acid | HCID 18512213 | — |
| Product | HCID 68855290 | HCID 68855290 | — |
Reaction Steps
The product from Example 100 (56 mg, 0.1 mmole) and H-Phe-OtBu HCl (52 mg, 0.2 mmole) were processed as in Example 213A-B to provide the title compound. 1H NMR (500 MHz, DMSO-d6) δ12.22-12.98 (br.s, 1 H), 8.95 (s, 1 H), 8.10 (d, 1 H), 7.22 (m, 12 H), 7.10 (d, 2 H), 7.04 (t, 1 H), 6.96 (m, 2 H), 6.87 (m, 4 H), 4.45 (m, 1 H), 4.06 (s, 2 H), 4.02 (s, 2 H), 3.06 (dd, 1 H), 2.91 (s, 3 H), 2.84 (dd, 1 H), 2.42 (t, 2 H), 2.39 (s, 3 H), 2.06 (m, 2 H), 1.68 (m, 2 H); MS (APCI+) m/z 706 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583180B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-dd231d01e8a64b0687bec2511ec1d472 |
| Source note | uspto-grants-2003_06 |