HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 7408333, compound → HCID 68857987, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 7408333 | HCID 7408333 | — |
| Reactant | 4-(4-{4-[(benzyl{2-methyl-3-[(methylsulfonyl)amino]phenyl}amino)methyl]phenoxy}phenyl)butanoic Acid | HCID 18512213 | — |
| Product | HCID 68857987 | HCID 68857987 | — |
Reaction Steps
The product from Example 100 (56 mg, 0.1 mmole) and H-D-Tyr-OtBu (47 mg, 0.2 mmole) were processed as in Example 213A-B to provide the title compound. 1H NMR (500 MHz, DMSO-d6) δ11.78-13.25 (br.s, 1 H), 8.95 (s, 1 H), 8.64-9.80 (br.s, 1 H), 8.03 (d, 1 H), 7.26 (m, 6 H), 7.19 (m, 1 H), 7.12 (d, 2 H), 7.00 (m, 5 H), 6.88 (m, 4 H), 6.64 (d, 2 H), 4.35 (m, 1 H), 4.06 (s, 2 H), 4.02 (s, 2 H), 2.94 (d, 1 H), 2.91 (s, 3 H), 2.72 (dd, 1 H), 2.44 (t, 2 H), 2.39 (s, 3 H), 2.06 (m, 2 H), 1.69 (m, 2 H); MS (APCI+) m/z 723 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583180B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-ca11e383b0e042e98a24fe418e438bed |
| Source note | uspto-grants-2003_06 |