HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl isoleucinate--hydrogen chloride (1/1) → HCID 68860208, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl isoleucinate--hydrogen chloride (1/1) | HCID 11687228 | — |
| Reactant | 4-(4-{4-[(benzyl{2-methyl-3-[(methylsulfonyl)amino]phenyl}amino)methyl]phenoxy}phenyl)butanoic Acid | HCID 18512213 | — |
| Product | HCID 68860208 | HCID 68860208 | — |
Reaction Steps
The product from Example 100 (56 mg, 0.1 mmole) and H-Ile-OtBu HCl (45 mg, 0.2 mmole) were processed as in Example 213A-B to provide the title compound. 1H NMR (500 MHz, DMSO-d6) δ11.81-12.98 (br.s, 1 H), 8.95 (s, 1 H), 7.93 (d, 1 H), 7.26 (m, 6 H), 7.18 (m, 3 H), 7.04 (t, 1 H), 6.96 (m, 2 H), 6.88 (d, 4 H), 4.19 (dd, 1 H), 4.05 (s, 2 H), 4.02 (s, 2 H), 2.91 (s, 3 H), 2.53 (t, 2 H), 2.39 (s, 3 H), 2.18 (m, 2 H), 1.76 (m, 3 H), 1.39 (m, 1 H), 1.20 (m, 1 H), 0.83 (m, 6 H); MS (APCI+) m/z 673 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583180B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-5c8dcf5bcd424dcc98c3b835fec7e5d5 |
| Source note | uspto-grants-2003_06 |