Sodium hydride → HCID 18510272, compound

Participants

Reaction Steps

To 1-(5-bromo-3-pyridinyl)-2-[4-(methylsulfanyl)phenyl]-1-ethanone in DMF (2.5 mL) at 0° C. was added NaH (15 mg, 0.5 mmole). The reaction was stirred 30 minutes, at which point cinnamyl bromide (0.1 g, 0.5 mmole) was added and the reaction was allowed to warm to room temperature. The reaction was quenched with H2O and extracted with ethyl acetate. The organic phase was dried (Na2SO4), filtered, and evaporated to give the title compound.

Provenance & Evidence