Sodium hydride → HCID 18510254, compound

Participants

Reaction Steps

To a solution of 2-[4-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]-1-phenyl 1-ethanone (0.2 g, 0.72 mmole) in DMF (3 mL) was added NaH (0.022 g, 0.7 mmole) at 0° C. The reaction was stirred for 15 min. Then a solution of cinnamyl bromide (0.16 g, 0.84 mmol) in 1 mL DMF was added. The reaction was warmed to room temperature, and was then quenched with saturated NH4Cl solution and extracted with ethyl acetate. The organic phase was then dried (Na2SO4), filtered, and evaporated to give the title compound.

Provenance & Evidence