Ethyl nipecotate → Ethyl 1-[2-tert-butyl-1-[(4,4-difluorocyclohexyl)methyl]benzimidazol-5-yl]sulfonylpiperidine-3-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]2[c:8]([n:9]1[CH2:10][CH:11]1[CH2:12][CH2:13][C:14]([F:17])([F:18])[CH2:15][CH2:16]1)[cH:19][cH:20][c:21]([S:23](=[O:24])(=[O:25])[Cl:26])[cH:22]2.[NH:27]1[CH2:28][CH:29]([C:33](=[O:34])[O:35][CH2:36][CH3:37])[CH2:30][CH2:31][CH2:32]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]2[c:8]([n:9]1[CH2:10][CH:11]1[CH2:12][CH2:13][C:14]([F:17])([F:18])[CH2:15][CH2:16]1)[cH:19][cH:20][c:21]([S:23](=[O:24])(=[O:25])[N:27]1[CH2:28][CH:29]([C:33](=[O:34])[O:35][CH2:36][CH3:37])[CH2:30][CH2:31][CH2:32]1)[cH:22]2Participants
3
Sources & evidence
- ORD record
- ord-6288a11c17c94299b1c241747e8ae540
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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