4-Morpholinecarbonyl chloride → HCID 10386873, compound

Participants

Reaction Steps

Using the general method of Example 149, 1-(3-aminopropyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine (1.0 g, 3.36 mmol) was reacted with 4-morpholinecarbonyl chloride (830 mg, 5.55 mmol) to provide 650 mg of N-[3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]morpholine-4-carboxamide as a white powder, m.p. 193.4–194.6° C. Analysis: Calculated for C22H30N6O2: % C, 64.37; % H, 7.37; % N, 20.47; Found: % C, 64.00; % H, 7.32; % N, 20.16.

Provenance & Evidence