Cyclohexyl isothiocyanate → HCID 10321045, compound

Participants

Reaction Steps

Using the general method of Example 149, 1-(3-aminopropyl)-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-4-amine (1.53 g, 5.11 mmol) was-reacted with cyclohexyl isothiocyanate (794 mg, 5.62 mmol) to provide 1.35 g of N-(3-[4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propyl}-N′-cyclohexylthiourea as a tan powder, m.p. 199–200° C. Analysis: Calculated for C23H32N6OS: % C, 62.70; % H, 7.32; % N, 19.07; Found: % C, 62.37; % H, 7.20; % N, 18.70.

Provenance & Evidence