Phenyl isocyanate → HCID 10251451, compound

Participants

Reaction Steps

Using the general method of Example 149, 1-(3-aminopropyl)-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-4-amine (1.50 g, 5.01 mmol) was reacted with phenyl isocyanate (660 mg, 5.51 mmol). Recrystallization from acetonitrile provided 670 mg of N-{3-[4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propyl)-N′-phenylurea as light orange needles, m.p. ˜40° C. Analysis: Calculated for C23H26N6O2. 1.0 C2H3N: % C, 65.34; % H, 6.36; % N, 21.34; Found: % C, 65.13; % H, 6.26; % N, 21.35.

Provenance & Evidence