Butyl isocyanate → HCID 10430989, compound

Participants

Reaction Steps

Using the general method of Example 149, 1-(3-aminopropyl)-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-4-amine (1.50 g, 5.01 mmol) was reacted with butyl isocyanate to provide 1.13 g of N-(3-[4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propyl}-N′-butylurea as an off-white powder, m.p. 159–160° C. Analysis: Calculated for C21H30N6O2.0.29 H2O: % C, 62.47; % H, 7.63; % N, 20.82; Found: % C, 62.64; % H, 7.58; % N, 21.17.

Provenance & Evidence