4-Morpholinecarbonyl chloride → HCID 10409430, compound

Participants

Reaction Steps

Using the general method of Example 143, 1-(3-aminopropyl)-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-4-amine (1.50 g, 5.01 mmol) was reacted with 4-morpholinecarbonyl chloride (830 mg, 5.51 mmol) to provide 1.6 g of N-{3-[4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propyl}morpholine-4-carboxamide as a white powder, m.p. 194–196° C. Analysis: Calculated for C21H28N6O3: % C, 61.15; % H, 6.84; % N, 20.37; Found: % C, 60.82; % H, 6.94; % N, 20.34.

Provenance & Evidence