4-Morpholinecarbonyl chloride → HCID 9843172, compound

Participants

Reaction Steps

Using the general method of Example 143, 1-(4-aminobutyl)-2-methyl-6,7,8,9-tetrahydro-1H-imidazo[4,5-c]quinolin-4-amine (1.00 g, 3.7 mmol) was reacted with 4-morpholinecarbonyl chloride (0.43 mL, 3.7 mmol) to provide 1.14 g of N-[4-(4-amino-2-methyl-6,7,8,9-tetrahydro-1H-imidazo[4,5-c]quinolin-1-yl)butyl]morpholine-4-carboxamide as an off white solid, m.p. 133.6–134.6° C. Analysis: Calculated for C20H30N6O2.1.1 H2O: % C, 59.12; % H, 7.99; % N, 20.68; Found: % C, 58.77; % H, 7.53; % N, 20.46.

Provenance & Evidence