Isocyanic acid, p-methoxybenzyl- → N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-N'-(4-methoxybenzyl)urea

Participants

Role	Name	HCID	Charge
Reactant	Isocyanic acid, p-methoxybenzyl-	HCID 187910	—
Reactant	[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine	HCID 10308229	—
Product	N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-N'-(4-methoxybenzyl)urea	HCID 10296863	—

Reaction Steps

Example 2 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 3 (0.025 g) and 1-(isocyanatomethyl)-4-methoxybenzene (19.5 μl) to give the title compound (0.0257 g). LC-MS (System A): Rt 2.23 mins, Mass Spectrum m/z 438 [MH+].

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07157457B2
Source dataset	uspto-grants-2007_01
ORD ID	ord-c70e9c4a363746a89a3b9c082aa4c99e
Source note	uspto-grants-2007_01