HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Isocyanatomethyl)-2-methylbenzene → N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-N'-(2-methylbenzyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Isocyanatomethyl)-2-methylbenzene | HCID 2733386 | — |
| Reactant | [4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine | HCID 10308229 | — |
| Product | N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-N'-(2-methylbenzyl)urea | HCID 17984656 | 70.1% |
Reaction Steps
Example 6 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 3 (0.025 g) and 1-(isocyanatomethyl)-2-methylbenzene (0.0201 g) to give the title compound (0.0269 g). LC-MS (System A): Rt 2.31 mins, Mass Spectrum m/z 422 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157457B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-8adceef716b44e1fbd9a9ec6e48afb6a |
| Source note | uspto-grants-2007_01 |