Cyclohexyl isocyanate → HCID 10272298, compound

HRID 1371408Notes

Reaction equation

HRID 1371408 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[Cl:17])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH2:13])[CH2:7]1.[N:18]([CH:21]1[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1)=[C:19]=[O:20]>>[CH:21]1([NH:18][C:19]([NH:13][CH2:12][CH:8]2[O:9][CH2:10][CH2:11][N:6]([CH2:5][C:4]3[CH:14]=[CH:15][C:16]([Cl:17])=[C:2]([Cl:1])[CH:3]=3)[CH2:7]2)=[O:20])[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1

Participants

3

Reactant 2

HCID 18502Cyclohexyl isocyanateHCID 10308229[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine

Product 1

HCID 10272298HCID 10272298, compound

Procedure

Example 7 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 3 (0.025 g) and isocyanatocyclohexane (17.4 μl) to give the title compound (0.0298 g). LC-MS (System A): Rt 2.26 mins, Mass Spectrum m/z 400 [MH+].

Workup

  1. customExample 7 was prepared in an analogous manner to Example 1 using

Sources & evidence

ORD record
ord-924d3a8714ce4279906688c31d50cfcc
Source dataset
uspto-grants-2007_01
Patent number
US07157457B2

Reaction notes

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